Adrenalectomy of the obese Zucker rat: effects on the feeding response to enterostatin and specific mRNA levels.

@article{Okada1993AdrenalectomyOT,
  title={Adrenalectomy of the obese Zucker rat: effects on the feeding response to enterostatin and specific mRNA levels.},
  author={Setsuro Okada and T Onai and Gail E. Kilroy and David A. York and George A. Bray},
  journal={The American journal of physiology},
  year={1993},
  volume={265 1 Pt 2},
  pages={R21-7}
}
The effects of adrenalectomy on the feeding response to enterostatin and the mRNA levels of its parent protein, pancreatic colipase, have been investigated in lean (fa/?) and genetically obese (fa/fa) rats. Adrenalectomy reduced body weight gain and food intake of obese rats. Enterostatin inhibited the intake of high-fat diet in obese rats but not in lean rats. Adrenalectomy reduced food intake of all rats and abolished the response to enterostatin in the obese group. Obese rats had low levels… CONTINUE READING