Adrenal steroids suppress granule cell death in the developing dentate gyrus through an NMDA receptor-dependent mechanism.

@article{Gould1997AdrenalSS,
  title={Adrenal steroids suppress granule cell death in the developing dentate gyrus through an NMDA receptor-dependent mechanism.},
  author={Elizabeth Gould and Patima Tanapat and Heather A. Cameron},
  journal={Brain research. Developmental brain research},
  year={1997},
  volume={103 1},
  pages={91-3}
}
Treatment with the NMDA receptor antagonist MK-801 prevented the adrenal steroid-induced suppression of cell death, determined by both morphological identification of pyknotic cells and TUNEL staining, in the dentate gyrus in rat pups. This finding suggests that adrenal steroids naturally promote granule cell survival via NMDA receptor activation. 

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