Adrenal necrosis in a dog receiving trilostane for the treatment of hyperadrenocorticism.

@article{Chapman2004AdrenalNI,
  title={Adrenal necrosis in a dog receiving trilostane for the treatment of hyperadrenocorticism.},
  author={Peter S Chapman and Donald F. Kelly and J. F. Archer and Daniel J Brockman and Reto Neiger},
  journal={The Journal of small animal practice},
  year={2004},
  volume={45 6},
  pages={307-10}
}
Clinical and biochemical changes suggestive of hypoadrenocorticism were observed in a 10-year-old male neutered Staffordshire bull terrier shortly after beginning therapy with trilostane for the treatment of hyperadrenocorticism. The dog's condition was stabilised with intravenous fluids, fludrocortisone and prednisolone. An exploratory laparotomy and excisional biopsy of the left adrenal gland were performed. Histopathological analysis showed adrenal cortical necrosis with reactive… CONTINUE READING

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