Adrenal apoplexy was revealed in 14.6% of the patients, who died after removal of meningiomas of the cerebral hemispheres. This complication more often occurred in basal location of a tumor. Manifestation of acute adrenal apoplexy in the majority of neurooncologic patients are atypical because of their general severe state after removal of a tumor. Adrenal apoplexy usually was associated with hemorrhagic and ischemic disorders in the central nervous system and internal organs and led to the death of patients. A search for the methods of investigation, permitting to prognosticate this complication is necessary.