Adrenal demedullation and peripheral 6-OHDA administration in the rabbit: effects on body weight, general activity and cardiovascular responsivity.

@article{Joseph1979AdrenalDA,
  title={Adrenal demedullation and peripheral 6-OHDA administration in the rabbit: effects on body weight, general activity and cardiovascular responsivity.},
  author={J. A. Joseph and William O. Boggan and Donald A. Powell},
  journal={Pharmacology, biochemistry, and behavior},
  year={1979},
  volume={10 6},
  pages={875-81}
}
Two experiments were undertaken to determine the effects of systemic 6-hydroxydopamine (6-OHDA) administration and adrenal enucleation on body weight, brain and heart norepinephrine, general activity, and cardiovascular responsivity in the rabbit. 6-Hydroxydopamine produced long lasting, dose related decreases in baseline blood pressure (BP) and in pressor… CONTINUE READING