Adrenal changes associated with adrenarche

@article{Nakamura2008AdrenalCA,
  title={Adrenal changes associated with adrenarche},
  author={Yasuhiro Nakamura and Hui Xiao Gang and Takashi Suzuki and Hironobu Sasano and William E. Rainey},
  journal={Reviews in Endocrine and Metabolic Disorders},
  year={2008},
  volume={10},
  pages={19-26}
}
The mechanisms causing the rise in adrenal androgen production during the course of adrenarche remain to be defined. However, the increase in steroid release is clearly associated with a series of intra-adrenal changes in the expression of steroidogenic enzymes needed for dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) production, as well as an expansion of the adrenal zona reticularis (ZR). We and others have defined the adrenal expression pattern of key steroidogenic… CONTINUE READING
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