Adoptive transfer of immunity to Nocardia asteroides in nude mice.

  title={Adoptive transfer of immunity to Nocardia asteroides in nude mice.},
  author={Richard L. Deem and Blaine L. Beaman and M Eric Gershwin},
  journal={Infection and immunity},
  volume={38 3},
Nude mice on a BALB/c background were adoptively transferred with unprimed spleen cells, Nocardia-primed spleen cells, or Nocardia-primed splenic T lymphocytes from syngeneic, heterozygous (nu/+) littermates. Two days later, these recipient mice and unmanipulated (control) nude mice were infected intravenously with a 50% lethal dose of Nocardia asteroides GUH-2 from an early stationary-phase culture. Antibody titers, spleen weights, percent mortality, and organ clearance of the microorganisms… CONTINUE READING

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