Adoptive immunotherapy of breast cancer with lymph node cells primed by cryoablation of the primary tumor.

@article{Sabel2006AdoptiveIO,
  title={Adoptive immunotherapy of breast cancer with lymph node cells primed by cryoablation of the primary tumor.},
  author={Michael S Sabel and Alisha Arora and Gang Su and Alfred E. Chang},
  journal={Cryobiology},
  year={2006},
  volume={53 3},
  pages={
          360-6
        }
}
Cryoablation of cancer leaves tumor-associated antigens intact in an inflammatory microenvironment that can stimulate a regional anti-tumor immune response. We examined whether cryoablated tumor draining lymph nodes (CTDLN) as adoptive immunotherapy may be an effective immunotherapeutic approach in the adjuvant treatment of breast cancer. BALB/c mice with MT-901 mammary adenocarcinoma tumors underwent cryoablation, resection or no treatment and tumor draining lymph nodes were harvested… CONTINUE READING

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  • 2019
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