Adolescent mice are more vulnerable than adults to single injection-induced behavioral sensitization to amphetamine

@article{Kameda2011AdolescentMA,
  title={Adolescent mice are more vulnerable than adults to single injection-induced behavioral sensitization to amphetamine},
  author={Sonia Regina Kameda and Daniela Fukue Fukushiro and Tha{\'i}s Fernanda Trombin and Roberta Proc{\'o}pio-Souza and Camilla de Lima Patti and Andre Willian Hollais and Mariana Bendlin Calzavara and Vanessa Costhek Ab{\'i}lio and Rosana de Alencar Ribeiro and Sergio Brasil Tufik and V{\~a}nia D'Almeida and Roberto Frussa-Filho},
  journal={Pharmacology Biochemistry and Behavior},
  year={2011},
  volume={98},
  pages={320-324}
}
Drug-induced behavioral sensitization in rodents has enhanced our understanding of why drugs acquire increasing motivational and incentive value. Compared to adults, human adolescents have accelerated dependence courses with shorter times from first exposure to dependence. We compared adolescent and adult mice in their ability to develop behavioral sensitization to amphetamine following a single injection. Adult (90-day-old) and adolescent (45-day-old) male Swiss mice received an acute… CONTINUE READING

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Highly Influenced

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