Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties.

@article{Chen2007AdolescentFH,
  title={Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties.},
  author={Xiongwen Chen and Rachel Marie Wilson and Hajime Kubo and Remus M. Berretta and David M. Harris and Xiaoying Zhang and Naser Jaleel and Scott M Macdonnell and Claudia Bearzi and Jochen Tillmanns and Irina Trofimova and Toru Hosoda and Federico Mosna and Leanne L. Cribbs and Annarosa Leri and Jan Kajstura and Piero Anversa and Steven R. Houser},
  journal={Circulation research},
  year={2007},
  volume={100 4},
  pages={
          536-44
        }
}
Recent studies suggest that rather than being terminally differentiated, the adult heart is a self-renewing organ with the capacity to generate new myocytes from cardiac stem/progenitor cells (CS/PCs). This study examined the hypotheses that new myocytes are generated during adolescent growth, to increase myocyte number, and these newly formed myocytes are initially small, mononucleated, proliferation competent, and have immature properties. Ventricular myocytes (VMs) and cKit(+) (stem cell… CONTINUE READING
Highly Cited
This paper has 78 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 53 extracted citations

Cardiac stem cells and myocardial disease.

Journal of molecular and cellular cardiology • 2008
View 4 Excerpts
Highly Influenced

Antiarrhythmic effect of growth factor-supplemented cardiac progenitor cells in chronic infarcted heart.

American journal of physiology. Heart and circulatory physiology • 2016
View 1 Excerpt

79 Citations

0510'09'12'15'18
Citations per Year
Semantic Scholar estimates that this publication has 79 citations based on the available data.

See our FAQ for additional information.