Adolescent ethanol sensitivity: hypothermia and acute tolerance.

A two-injection paradigm was used to assess acute (within-session) tolerance to ethanol in telemetry-implanted adolescent and adult rats. Male rats were intragastrically pretreated with either 1.0 g/kg of ethanol or water and then challenged with 2.0 g/kg of ethanol or water when blood alcohol levels (BALs) of ethanol-pretreated animals were anticipated to… (More)