Adolescent chronic stress causes hypothalamo–pituitary–adrenocortical hypo-responsiveness and depression-like behavior in adult female rats

@article{Wulsin2016AdolescentCS,
  title={Adolescent chronic stress causes hypothalamo–pituitary–adrenocortical hypo-responsiveness and depression-like behavior in adult female rats},
  author={A. Wulsin and Dayna Wick-Carlson and B. Packard and Rachel L. Morano and J. Herman},
  journal={Psychoneuroendocrinology},
  year={2016},
  volume={65},
  pages={109-117}
}
Adolescence is a period of substantial neuroplasticity in stress regulatory neurocircuits. Chronic stress exposure during this period leads to long-lasting changes in neuroendocrine function and emotional behaviors, suggesting adolescence may be a critical period for development of stress vulnerability. This study investigated the effects of exposure to 14 days of chronic variable stress (CVS) in late-adolescent (pnd 45-58) female rats on neuroendocrine function, neuropeptide mRNA expression… Expand
Long-term impact of chronic variable stress in adolescence versus adulthood
Adolescence and the ontogeny of the hormonal stress response in male and female rats and mice
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