Adolescent and Young Adult (AYA) Oncology in the United States: A Specialty in Its Late Adolescence

@article{Shaw2015AdolescentAY,
  title={Adolescent and Young Adult (AYA) Oncology in the United States: A Specialty in Its Late Adolescence},
  author={Peter H Shaw and Damon R. Reed and Nicholas D. Yeager and Brad Zebrack and Sharon M Castellino and Archie Bleyer},
  journal={Journal of Pediatric Hematology/Oncology},
  year={2015},
  volume={37},
  pages={161–169}
}
Over the last 30 years, it has become apparent that oncology patients ages 15 to 39 have not reaped the same rewards of improved survival that we have seen in younger and older patients. As a result, in 2006 the Adolescent and Young Adult (AYA) Oncology Progress Review Group convened and examined the factors that impact the care of the 70,000 new cases per year (approximately 7% of all new cases) in the United States and published their findings. The reasons for inferior survival gains are of… 
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51 Citations
Background Citations
20
Methods Citations
1
Results Citations
2

51 Citations

Disparities in Adolescents and Young Adults With Cancer

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Recent progress in AYA patient care is discussed and remaining disparities that exist are highlighted, including financial disadvantages, need for fertility care, limited clinical trial availability, and other areas of evolving AYA-focused research are highlighted.

AYA Considerations for Aggressive Lymphomas

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There is an urgent need for clinical trials including AYAs in order to increase the knowledge of age-specific outcomes, toxicities, disease biology, and the need to develop comprehensive AYA care models that meet the unique and complex care needs of this patient population.

Adolescent and young adult lymphoma: collaborative efforts toward optimizing care and improving outcomes.

TLDR
An in-depth discussion of lymphoma management across pediatric and adult oncologic disciplines, focusing on Hodgkin lymphoma, mature B-cell lymphomas, and anaplastic large cell lymphoma is presented.

Palliative Care in Adolescents and Young Adults With Cancer.

TLDR
The emerging trend toward standardizing oncology care to meet the unique medical, psychosocial, and supportive care needs of AYA patients with cancer and their families represents an opportunity for health care professionals to collaborate early with palliative care specialists to control symptoms and relieve suffering in this vulnerable population.

Current considerations in AYA Hodgkin lymphoma

TLDR
Current prognostic and treatment strategies for paediatric and adult patients with HL are reviewed and complexities around the management of this patient population are highlighted.

Survival after cancer in children, adolescents and young adults in the Nordic countries from 1980 to 2013

TLDR
It is suggested that in an affluent setting with free access to healthcare, meaningful differences in survival between AYA patients and either childhood or adult patients are a phenomenon of the past for most AYA cancer diagnostic groups.

Trends in Cancer Mortality Among Adolescents and Young Adults in Brazil.

TLDR
The aim of this study was to evaluate the trends in cancer mortality of AYA aged 15–29 years in Brazil and found that survival among this group has not improved as much as in younger children with cancer.

Outcomes of Lymphoma Among American Adolescent and Young Adult Patients Varied by Health Insurance—A SEER-based Study

TLDR
No or insufficient insurance was linked to poor OS in the authors' sample in exposure-outcome association analysis, suggesting insurance coverage and health care availability may enhance disparate outcomes of AYAs with cancer.

Enrollment of adolescents and young adults onto SWOG cancer research network clinical trials: A comparative analysis by treatment site and era

Few adolescents and young adults (AYAs, 15‐39 years old) enroll onto cancer clinical trials, which hinders research otherwise having the potential to improve outcomes in this unique population. Prior…

The feasibility and value of parent input when evaluating the mental health of young adults with and without cancer

TLDR
Whether the K-SADS-PL could be extended to young adults 18 to 25 with and without cancer by assessing the feasibility of obtaining parent interviews, and furthermore, whether parent interviews improved the detection of mental health symptoms compared with young adult interviews alone.
...

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