Adolescent γ-hydroxybutyric acid exposure decreases cortical N-methyl-d-aspartate receptor and impairs spatial learning

@article{Sircar2004AdolescentA,
  title={Adolescent γ-hydroxybutyric acid exposure decreases cortical N-methyl-d-aspartate receptor and impairs spatial learning},
  author={R. Sircar and A. Basak},
  journal={Pharmacology Biochemistry and Behavior},
  year={2004},
  volume={79},
  pages={701-708}
}
  • R. Sircar, A. Basak
  • Published 2004
  • Psychology, Medicine
  • Pharmacology Biochemistry and Behavior
  • gamma-hydroxybutyric acid (GHB), which belongs to the class of substances referred to as "club drugs", is abused for its euphoric, sedative and anabolic effects. GHB use and abuse is most prevalent among adolescents and young adults. In almost all cases of GHB abuse, subjects report of amnesia. Behavioral effects of GHB in animals, particularly on learning and memory are not known. In this study, effects of GHB exposure on spatial learning and memory in adolescent rats were tested using the… CONTINUE READING
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