Admixture in Mexico City: implications for admixture mapping of Type 2 diabetes genetic risk factors

@article{MartnezMarignac2006AdmixtureIM,
  title={Admixture in Mexico City: implications for admixture mapping of Type 2 diabetes genetic risk factors},
  author={Ver{\'o}nica L. Mart{\'i}nez-Marignac and Ad{\'a}n Valladares and Emily Cameron and Andrea Chan and Arjuna Perera and Rachel Globus-Goldberg and Niels H Wacher and Jes{\'u}s Kumate and Paul M. McKeigue and David O'donnell and Mark David Shriver and Miguel Cruz and Esteban Juan Parra},
  journal={Human Genetics},
  year={2006},
  volume={120},
  pages={807-819}
}
Admixture mapping is a recently developed method for identifying genetic risk factors involved in complex traits or diseases showing prevalence differences between major continental groups. Type 2 diabetes (T2D) is at least twice as prevalent in Native American populations as in populations of European ancestry, so admixture mapping is well suited to study the genetic basis of this complex disease. We have characterized the admixture proportions in a sample of 286 unrelated T2D patients and 275… 

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