Admission Hematocrit and Rise in Blood Urea Nitrogen at 24 h Outperform other Laboratory Markers in Predicting Persistent Organ Failure and Pancreatic Necrosis in Acute Pancreatitis: A Post Hoc Analysis of Three Large Prospective Databases

@article{Koutroumpakis2015AdmissionHA,
  title={Admission Hematocrit and Rise in Blood Urea Nitrogen at 24 h Outperform other Laboratory Markers in Predicting Persistent Organ Failure and Pancreatic Necrosis in Acute Pancreatitis: A Post Hoc Analysis of Three Large Prospective Databases},
  author={Efstratios I Koutroumpakis and Bechien U. Wu and Olaf J. Bakker and Anwar Dudekula and Vikesh K. Singh and Marc G. H. Besselink and Dhiraj Yadav and Hjalmar C. van Santvoort and David C. Whitcomb and H. G. Gooszen and Peter A. Banks and Georgios Ioannis Papachristou},
  journal={The American Journal of Gastroenterology},
  year={2015},
  volume={110},
  pages={1707-1716}
}
OBJECTIVES:Predicting severe acute pancreatitis (AP) remains a challenge. The present study compares admission blood urea nitrogen (BUN), hematocrit, and creatinine, as well as changes in their levels over 24 h, aiming to determine the most accurate laboratory test for predicting persistent organ failure and pancreatic necrosis.METHODS:Clinical data of 1,612 AP patients, enrolled prospectively in three independent cohorts (University of Pittsburgh, Brigham and Women’s Hospital, Dutch… CONTINUE READING
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