Administrations of peripheral blood CD34-positive cells contribute to medial collateral ligament healing via vasculogenesis.

@article{Tei2008AdministrationsOP,
  title={Administrations of peripheral blood CD34-positive cells contribute to medial collateral ligament healing via vasculogenesis.},
  author={Katsumasa Tei and Tomoyuki Matsumoto and Yutaka Mifune and Kazunari Ishida and Ken Sasaki and Taro Shoji and Seiji Kubo and Atsuhiko Kawamoto and Takayuki Asahara and Masahiro Kurosaka and Ryosuke Kuroda},
  journal={Stem cells},
  year={2008},
  volume={26 3},
  pages={819-30}
}
Neoangiogenesis is a key process in the initial phase of ligament healing. Adult human circulating CD34+ cells, an endothelial/hematopoietic progenitor-enriched cell population, have been reported to contribute to neoangiogenesis; however, the therapeutic potential of CD34+ cells for ligament healing is still unclear. Therefore, we performed a series of experiments to test our hypothesis that ligament healing is supported by CD34+ cells via vasculogenesis. Granulocyte colony-stimulating factor… CONTINUE READING
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