Administration-time-dependent effects of hypertension treatment on ambulatory blood pressure in patients with chronic kidney disease.

@article{Crespo2013AdministrationtimedependentEO,
  title={Administration-time-dependent effects of hypertension treatment on ambulatory blood pressure in patients with chronic kidney disease.},
  author={Juan J. Crespo and Luis D. Pi{\~n}eiro and Alfonso Romero Otero and Carmen Casti{\~n}eira and M T Montoro R{\'i}os and Antonio Regueiro and Artemio Moj{\'o}n and Sonia Lorenzo and Diana Elva Ayala and Ram{\'o}n C. Hermida},
  journal={Chronobiology international},
  year={2013},
  volume={30 1-2},
  pages={159-75}
}
Many published prospective trials have reported clinically meaningful morning-evening, treatment-time differences in the blood pressure (BP)-lowering efficacy, duration of action, and safety of most classes of hypertension medications. Most important, it was recently documented that routine ingestion of the full daily dose of ≥1 hypertension medications at… CONTINUE READING