Administration of pigment epithelium-derived factor inhibits left ventricular remodeling and improves cardiac function in rats with acute myocardial infarction.

Abstract

Oxidative stress and inflammation are involved in cardiac remodeling after acute myocardial infarction (AMI). We have found that pigment epithelium-derived factor (PEDF) inhibits vascular inflammation through its anti-oxidative properties. However, effects of PEDF on cardiac remodeling after AMI remain unknown. We investigated whether PEDF could inhibit… (More)
DOI: 10.1016/j.ajpath.2010.10.018

Topics

Cite this paper

@article{Ueda2011AdministrationOP, title={Administration of pigment epithelium-derived factor inhibits left ventricular remodeling and improves cardiac function in rats with acute myocardial infarction.}, author={Shin-ichiro Ueda and Sho-ichi Yamagishi and Takanori Matsui and Yuko Jinnouchi and Tsutomu Imaizumi}, journal={The American journal of pathology}, year={2011}, volume={178 2}, pages={591-8} }