Administration of novel dyes for intraocular surgery: an in vivo toxicity animal study.

  title={Administration of novel dyes for intraocular surgery: an in vivo toxicity animal study.},
  author={Frank Schuettauf and Christos Haritoglou and Christian Albrecht May and Robert Rejdak and Anna Mańkowska and Wolfgang Freyer and Kirsten H Eibl and Eberhart Zrenner and Anselm Kampik and Sebastian Thaler},
  journal={Investigative ophthalmology & visual science},
  volume={47 8},
PURPOSE To investigate the effect of intravitreal injections of new vital dyes on the retina, the retinal pigment epithelium (RPE) and the choroid in an in vivo rat model. METHODS Rats were injected intravitreally with four dyes: light-green SF yellowish (LGSF), copper(II)phthalocyanine-tetrasulfonic acid (E68), bromphenol blue (BPB), and Chicago blue (CB) dissolved in physiologic saline solution (PSS) at concentrations of 0.5% and 0.02%. PSS served as the control. Additional animals were… CONTINUE READING


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An evaluation of novel vital dyes for intraocular surgery.

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