Administration of l-2-oxothiazolidine-4-carboxylate increases glutathione levels in rat brain

@article{Mesina1989AdministrationOL,
  title={Administration of l-2-oxothiazolidine-4-carboxylate increases glutathione levels in rat brain},
  author={J. E. Mesina and Richard H. Page and Fred W. Hetzel and Michael Chopp},
  journal={Brain Research},
  year={1989},
  volume={478},
  pages={181-183}
}
Sterile L-2-oxothiazolidine-4-carboxylate, given as a neutral 100 mmol solution at a dose of 8 mmol/kg subcutaneously, caused an increase in total glutathione concentration in the brain of treated rats. This finding could be important in understanding the role of glutathione in the central nervous system. 

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Metabolism and functions of glutathione in brain

  • Progress in Neurobiology
  • 2000
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