Administration of ketamine for unipolar and bipolar depression

  title={Administration of ketamine for unipolar and bipolar depression},
  author={C. Kraus and Ulrich Rabl and T. Vanicek and L. Carlberg and A. Popovi{\'c} and M. Spies and L. Bartova and G. Gryglewski and K. Papageorgiou and R. Lanzenberger and M. Willeit and D. Winkler and J. Rybakowski and S. Kasper},
  journal={International Journal of Psychiatry in Clinical Practice},
  pages={12 - 2}
  • C. Kraus, Ulrich Rabl, +11 authors S. Kasper
  • Published 2017
  • Psychology, Medicine
  • International Journal of Psychiatry in Clinical Practice
  • Abstract Objective: Clinical trials demonstrated that ketamine exhibits rapid antidepressant efficacy when administered in subanaesthetic dosages. We reviewed currently available literature investigating efficacy, response rates and safety profile. Methods: Twelve studies investigating unipolar, seven on bipolar depression were included after search in medline, scopus and web of science. Results: Randomized, placebo-controlled or open-label trials reported antidepressant response rates after 24… CONTINUE READING
    41 Citations
    Ketamine for Depression, 2: Diagnostic and Contextual Indications.
    • C. Andrade
    • Psychology, Medicine
    • The Journal of clinical psychiatry
    • 2017
    • 12
    • PDF
    Low-dose ketamine for treatment resistant depression in an academic clinical practice setting.
    • 13
    • PDF
    Ketamine and Treatment-Resistant Depression.
    • 1
    • Highly Influenced
    Novel Therapeutics in Bipolar Disorder
    • 1
    Pharmacological Treatment of Bipolar Depression: What are the Current and Emerging Options?
    • PDF


    A Randomized Controlled Trial of Intranasal Ketamine in Major Depressive Disorder
    • 282
    • Highly Influential
    • PDF
    Do the dissociative side effects of ketamine mediate its antidepressant effects?
    • 150
    • PDF
    Ketamine safety and tolerability in clinical trials for treatment-resistant depression.
    • 118
    • Highly Influential
    • PDF
    Rapid Antidepressant Response with Ketamine: Is it the Solution to Resistant Depression?
    • 17
    • Highly Influential
    Ketamine for rapid reduction of suicidal ideation: a randomized controlled trial.
    • 143
    Relationship of ketamine's antidepressant and psychotomimetic effects in unipolar depression.
    • 135
    • Highly Influential
    • PDF