Administration of ketamine for unipolar and bipolar depression
@article{Kraus2017AdministrationOK, title={Administration of ketamine for unipolar and bipolar depression}, author={C. Kraus and Ulrich Rabl and T. Vanicek and L. Carlberg and A. Popovi{\'c} and M. Spies and L. Bartova and G. Gryglewski and K. Papageorgiou and R. Lanzenberger and M. Willeit and D. Winkler and J. Rybakowski and S. Kasper}, journal={International Journal of Psychiatry in Clinical Practice}, year={2017}, volume={21}, pages={12 - 2} }
Abstract Objective: Clinical trials demonstrated that ketamine exhibits rapid antidepressant efficacy when administered in subanaesthetic dosages. We reviewed currently available literature investigating efficacy, response rates and safety profile. Methods: Twelve studies investigating unipolar, seven on bipolar depression were included after search in medline, scopus and web of science. Results: Randomized, placebo-controlled or open-label trials reported antidepressant response rates after 24… CONTINUE READING
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