Administration of high doses of caffeine increases alveolar bone loss in ligature-induced periodontitis in rats.

Abstract

BACKGROUND Although some studies have reported a negative influence of caffeine on bone metabolism, there is no information about its effect on the progression of periodontitis. The aim of this study was to evaluate the effect of high doses of caffeine on ligature-induced periodontitis in rats. METHODS Twenty-two Wistar rats were assigned to one of the… (More)
DOI: 10.1902/jop.2008.080204

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