Administration of Piceatannol Complexed with α-Cyclodextrin Improves Its Absorption in Rats.

@article{Inagaki2016AdministrationOP,
  title={Administration of Piceatannol Complexed with α-Cyclodextrin Improves Its Absorption in Rats.},
  author={Hiroyuki Inagaki and Ryouichi Ito and Yuko Setoguchi and Yukihiro Oritani and Tatsuhiko Ito},
  journal={Journal of agricultural and food chemistry},
  year={2016},
  volume={64 18},
  pages={3557-63}
}
Piceatannol is polyphenolic antioxidant found in passion fruit (Passiflora edulis) seeds. The aim of this study was to improve the absorption of piceatannol using α-cyclodextrin (αCD). The solubility of piceatannol in neutral and acidic solutions increased in an αCD concentration-dependent manner. The maximum plasma concentration of intact piceatannol and the time-to-maximum plasma concentration of O-methylated piceatannol metabolites increased in rats administered αCD-piceatannol inclusion… CONTINUE READING