Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs.

@article{Wang2006AdministrationOP,
  title={Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs.},
  author={Haijuan Wang and Haili Qian and Jian Ning Yu and Xueyan Zhang and Lin Zhang and Ming Fu and Xiao Liang and Qimin Zhan and Chen Lin},
  journal={Cancer biology & therapy},
  year={2006},
  volume={5 4},
  pages={380-5}
}
Esophageal cancer is one of the most lethal human tumors, characterized by relative chemoresistance and poor prognosis. Researchers have been seeking for multimodality to improve its outcome of therapy. PUMA (p53 upregulated modulator of apoptosis) is a potent proapoptotic molecule that is rapidly induced in cells following DNA damage and is required for p53-induced apoptosis. We evaluated the therapeutic potential of PUMA adenovirus against esophageal cancer cell lines (KYSE-150, KYSE-410… CONTINUE READING
21 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…