Administration of 6-gingerol greatly enhances the number of tumor-infiltrating lymphocytes in murine tumors.

@article{Ju2012AdministrationO6,
  title={Administration of 6-gingerol greatly enhances the number of tumor-infiltrating lymphocytes in murine tumors.},
  author={Seong-A. Ju and Sang-Min Park and Yea-Sol Lee and Jun-hyeong Bae and Rina Yu and Won Geun An and James Suh and Byung-sam Kim},
  journal={International journal of cancer},
  year={2012},
  volume={130 11},
  pages={
          2618-28
        }
}
Tumor-infiltrating lymphocytes (TILs) play critical roles in host antitumor immune responses. It is known that cancer patients with tumor-reactive lymphocyte infiltration in their tumors have better prognoses, while patients with tumors infiltrated by immunosuppressive cells have worse prognoses. We found that administration of 6-gingerol, which is a component of ginger, inhibited tumor growth in several types of murine tumors, such as B16F1 melanomas, Renca renal cell carcinomas and CT26 colon… CONTINUE READING
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