Administration, distribution, metabolism and elimination of polymer therapeutics.

@article{Markovsky2012AdministrationDM,
  title={Administration, distribution, metabolism and elimination of polymer therapeutics.},
  author={Ela Markovsky and Hemda Baabur-Cohen and Anat Eldar-Boock and Liora Omer and Galia Tiram and Shiran Ferber and Paula Ofek and Dina Polyak and Anna Scomparin and Ronit Satchi-Fainaro},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2012},
  volume={161 2},
  pages={
          446-60
        }
}
Polymer conjugation is an efficient approach to improve the delivery of drugs and biological agents, both by protecting the body from the drug (by improving biodistribution and reducing toxicity) and by protecting the drug from the body (by preventing degradation and enhancing cellular uptake). This review discusses the journey that polymer therapeutics make through the body, following the ADME (absorption, distribution, metabolism, excretion) concept. The biological factors and delivery system… CONTINUE READING

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