Administering 25-hydroxyvitamin D3 in vitamin D-deficient young type 1A diabetic patients reduces reactivity against islet autoantigens.

@article{Federico2014Administering2D,
  title={Administering 25-hydroxyvitamin D3 in vitamin D-deficient young type 1A diabetic patients reduces reactivity against islet autoantigens.},
  author={Giovanni Federico and Daniele Focosi and Benedetta Marchi and Emioli Randazzo and Monica De Donno and Francesco Vierucci and Marco Bugliani and Fabrizio Campi and Fabrizio Scatena and Giuseppe Saggese and Chantal Mathieu and Piero Marchetti},
  journal={Clinical nutrition},
  year={2014},
  volume={33 6},
  pages={1153-6}
}
BACKGROUND & AIMS We investigated whether improving 25-hydroxyvitamin D status in young type 1A diabetic patients reduces reactivity of peripheral blood mononuclear cells against islet autoantigens and associates with beta-cell functional changes. METHODS Eight patients with 25-hydroxyvitamin D deficiency (<20 ng/ml), out of 15 consecutive young type 1A… CONTINUE READING