Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii
@article{Iranshahy2014AdlumiceineME, title={Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii}, author={Milad Iranshahy and Hamideh Javidi-Shirazi and N. Pham and R. Quinn and H. Sadeghian and M. Iranshahi}, journal={Journal of Asian Natural Products Research}, year={2014}, volume={16}, pages={1148 - 1152} }
A new alkaloid, adlumiceine methyl ester (1), together with two known alkaloids, parfumine (2) and N-methylhydrastine methyl ester (3), was isolated from aerial parts of Fumaria vaillantii. The structures of compounds were determined by 1D/2D NMR and MS data. All three compounds were tested for cytotoxic activity against PC3 and MCF7 cell lines using Alamar blue assay. The tested compounds showed no significant cytotoxic activity (IC50>50 μM) against PC3 and MCF7 cell lines.
Topics from this paper
3 Citations
Diverse alkaloids and biological activities of Fumaria (Papaveraceae): An ethnomedicinal group.
- Biology, Medicine
- Fitoterapia
- 2020
Cytotoxicity and apoptosis induction by Fumaria officinalis extracts in leukemia and multiple myeloma cell lines.
- Chemistry, Medicine
- Journal of ethnopharmacology
- 2020
References
SHOWING 1-10 OF 26 REFERENCES
The anti-cancer activity of noscapine: a review.
- Medicine
- Recent patents on anti-cancer drug discovery
- 2009
- 83
Biologically active isoquinoline alkaloids with drug-like properties from the genus Corydalis
- Biology
- 2014
- 46
- PDF
Benzylisoquinoline alkaloids from the papaveraceae: the heritage of Johannes Gadamer (1867-1928).
- Medicine
- Journal of natural products
- 2011
- 11
- PDF
Potent cytotoxic effects of Calomeria amaranthoides on ovarian cancers
- Medicine
- Journal of experimental & clinical cancer research : CR
- 2011
- 14
- PDF
Indian J
- Nat. Prod. Resour. 4, 81
- 2013
Int
- J. Pharmacol. 8, 177
- 2012