Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study.

@article{Kocher2011AdjuvantWR,
  title={Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study.},
  author={Martin Kocher and Riccardo Soffietti and Ufuk M Abacioglu and Salvador Vill{\'a} and François Fauchon and Brigitta G. Baumert and Laura Fariselli and Tzahala Tzuk-Shina and Rolf Dieter Kortmann and Christian Carrie and Mohamed Ben Hassel and Mauri Kouri and Egils Valeinis and Dirk van den Berge and Sandra Collette and Laurence Collette and R P Mueller},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2011},
  volume={29 2},
  pages={134-41}
}
PURPOSE This European Organisation for Research and Treatment of Cancer phase III trial assesses whether adjuvant whole-brain radiotherapy (WBRT) increases the duration of functional independence after surgery or radiosurgery of brain metastases. PATIENTS AND METHODS Patients with one to three brain metastases of solid tumors (small-cell lung cancer excluded) with stable systemic disease or asymptomatic primary tumors and WHO performance status (PS) of 0 to 2 were treated with complete… CONTINUE READING
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