Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor.


PURPOSE To evaluate granulocyte-macrophage colony-stimulating factor (GM-CSF) as surgical adjuvant therapy in patients with malignant melanoma who are at high risk of recurrence. PATIENTS AND METHODS Forty-eight assessable patients with stage III or IV melanoma were treated in a phase II trial with long-term, chronic, intermittent GM-CSF after surgical… (More)


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