Adjuvant therapy of malignant melanoma.

  title={Adjuvant therapy of malignant melanoma.},
  author={R Molife and Barry William Hancock},
  journal={Critical reviews in oncology/hematology},
  volume={44 1},
High risk surgically resected melanoma is associated with a less than 50% 5-year survival. Adjuvant therapy is an appropriate treatment modality in this setting, and is more likely to be effective as the tumour burden here is small. Clinical observations of spontaneous tumour regressions and a highly variable rate of disease progression suggest a role of the immune system in the natural history of melanoma. Biological agents have therefore been the subjects of numerous adjuvant studies. Early… CONTINUE READING


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