Adjuvant radiotherapy following radical prostatectomy for pathologic T3 or margin-positive prostate cancer: a systematic review and meta-analysis.

@article{Morgan2008AdjuvantRF,
  title={Adjuvant radiotherapy following radical prostatectomy for pathologic T3 or margin-positive prostate cancer: a systematic review and meta-analysis.},
  author={Scott C. Morgan and Tricia S Waldron and Libni J. Eapen and Linda A Mayhew and Eric William Winquist and Himu R Lukka},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={2008},
  volume={88 1},
  pages={1-9}
}
BACKGROUND AND PURPOSE Results following radical prostatectomy (RP) are suboptimal in patients found to have cancer extending beyond the prostatic capsule (pT3) or present at the resection margins (R1). The optimal postoperative management of such patients is undefined. Therapeutic alternatives include adjuvant radiotherapy (RT) or active surveillance. METHODS Randomized controlled trials (RCTs) were eligible for inclusion in this systematic review if they compared adjuvant RT in the… CONTINUE READING