Adjuvant radiation therapy for high-risk nodal metastases from cutaneous melanoma.

@article{Guadagnolo2009AdjuvantRT,
  title={Adjuvant radiation therapy for high-risk nodal metastases from cutaneous melanoma.},
  author={Beverly Ashleigh Guadagnolo and Gunar K. Zagars},
  journal={The Lancet. Oncology},
  year={2009},
  volume={10 4},
  pages={
          409-16
        }
}
The role of radiotherapy for nodal metastases from malignant melanoma is controversial. In patients with features that indicate high risk of recurrence of nodal disease, adjuvant irradiation lowers recurrence rates. High-risk features include extranodal spread of melanoma, more than two positive lymph nodes, large nodal size, or recurrent disease in previously dissected nodal basin. Data from randomised trials that confirm a benefit of adjuvant radiotherapy in patients with nodal disease at… CONTINUE READING

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