Adjuvant effect ofBacillus firmus in intranasal immunization of guinea pigs with inactivated type B influenza virus

Abstract

Intranasal immunization of guinea pigs with inactivated type B influenza virus plus inactivatedBacillus firmus as an adjuvant compared to the virus alone yields higher titers of serum hemagglutination-inhibiting antibodies and virus-neutralizing antibodies. This phenomenon could be useful in standard serology, especially in the preparation of immune sera against highly pathogenic strains forin vitro diagnosis.

DOI: 10.1007/BF02932172

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Cite this paper

@article{Havlkov2008AdjuvantEO, title={Adjuvant effect ofBacillus firmus in intranasal immunization of guinea pigs with inactivated type B influenza virus}, author={Martina Havl{\'i}{\vc}kov{\'a} and Ludmila Proke{\vs}ov{\'a} and Peter Zanvit and Jaroslav T{\'a}cner and Radom{\'i}ra Limberkov{\'a}}, journal={Folia Microbiologica}, year={2008}, volume={51}, pages={154-156} }