Adjuvant chemotherapy in muscle-invasive bladder carcinoma: a pooled analysis from phase III studies.

@article{Ruggeri2006AdjuvantCI,
  title={Adjuvant chemotherapy in muscle-invasive bladder carcinoma: a pooled analysis from phase III studies.},
  author={Enzo Maria Ruggeri and Diana Giannarelli and Emilio Bria and Paolo Carlini and Alessandra Felici and Fabrizio Nelli and Michele Gallucci and Francesco Cognetti and Camillo Francesco Pollera},
  journal={Cancer},
  year={2006},
  volume={106 4},
  pages={783-8}
}
BACKGROUND The treatment of muscle-invasive bladder carcinoma should include both the eradication of local disease and the elimination of potential micrometastases. To date, the 'gold standard' treatment for muscle invasive bladder carcinoma has been recognized to be radical cystectomy. Adjuvant chemotherapy (AC) has the advantage of being administered to patients with known prognostic factors of recurrence. A pooled analysis was used to verify whether AC is able to increase the disease-free… CONTINUE READING

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