Adjuvant chemotherapy in colorectal cancer: a joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group.

@article{Glimelius2005AdjuvantCI,
  title={Adjuvant chemotherapy in colorectal cancer: a joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group.},
  author={Bengt Glimelius and Olav Dahl and Bj{\"o}rn Cedermark and Anders Jakobsen and S\oren M\oller Bentzen and Hans Starkhammar and Henrik Gr{\"o}nberg and Ragnar Hultborn and Maria Albertsson and Lars A P{\aa}hlman and K. M. Tveit},
  journal={Acta oncologica},
  year={2005},
  volume={44 8},
  pages={904-12}
}
Due to uncertainties regarding clinically meaningful gains from adjuvant chemotherapy after colorectal cancer surgery, several Nordic Groups in the early 1990s initiated randomised trials to prove or reject such gains. This report gives the joint analyses after a minimum 5-year follow-up. Between October 1991 and December 1997, 2 224 patients under 76 years of age with colorectal cancer stages II and III were randomised to surgery alone (n = 1 121) or adjuvant chemotherapy (n = 1 103) which… CONTINUE READING