Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: a pooled analysis of two randomized trials.

@article{Mitry2008AdjuvantCA,
  title={Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: a pooled analysis of two randomized trials.},
  author={Emmanuel Mitry and Anthony L. A. Fields and Harry Bleiberg and Roberto Labianca and Guillaume Portier and Dongsheng Tu and Donato Nitti and Valter Torri and Dominique Elias and C O'callaghan and Bernard Langer and Giancarlo Martignoni and Olivier Bouch{\'e} and Franck Lazorthes and Eric Van Cutsem and Laurent Bedenne and Malcolm J. Moore and Philippe Rougier},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2008},
  volume={26 30},
  pages={4906-11}
}
PURPOSE Adjuvant systemic chemotherapy administered after surgical resection of colorectal cancer metastases may reduce the risk of recurrence and improve survival, but its benefit has never been demonstrated. Two phase III trials (Fédération Francophone de Cancérologie Digestive [FFCD] Trial 9002 and the European Organisation for Research and Treatment of Cancer/National Cancer Institute of Canada Clinical Trials Group/Gruppo Italiano di Valutazione Interventi in Oncologia [ENG] trial) used a… CONTINUE READING

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