Adjuvant Quil A improves protection in mice and enhances opsonic capacity of antisera induced by pneumococcal polysaccharide conjugate vaccines.

@article{DeVelasco1994AdjuvantQA,
  title={Adjuvant Quil A improves protection in mice and enhances opsonic capacity of antisera induced by pneumococcal polysaccharide conjugate vaccines.},
  author={E A DeVelasco and Huberta A. T. Dekker and P{\'e}ter Antal and Kees Jalink and Jos A. G. van Strijp and Andr{\'e} F. M. Verheul and Jan Verhoef and Harm Wouter Snippe},
  journal={Vaccine},
  year={1994},
  volume={12 15},
  pages={
          1419-22
        }
}
The adjuvant effect of Quil A on the primary antibody response of mice to pneumococcal capsular polysaccharide conjugates was examined. Quil A increased the anti-capsular polysaccharide antibody titres, the protection against Streptococcus pneumoniae, and the opsonic capacity of the antibodies as measured in a newly developed in vitro phagocytosis assay… CONTINUE READING