Adjusting for measurement error to assess health effects of variability in biomarkers. Multicenter AIDS Cohort Study.

@article{Lyles1999AdjustingFM,
  title={Adjusting for measurement error to assess health effects of variability in biomarkers. Multicenter AIDS Cohort Study.},
  author={Robert H Lyles and Alvaro Muňoz and Jinfeng Xu and Jeremy M. G. Taylor and Joan S Chmiel},
  journal={Statistics in medicine},
  year={1999},
  volume={18 9},
  pages={1069-86}
}
Longitudinal studies of health effects often relate individuals' biomarker levels to disease progression. Repeated measurements also provide an opportunity to assess within-individual biomarker variability, and it is reasonable to postulate that this measure might provide additional information about a particular outcome variable. Given the existing precedent for application of adjustment methods to account for measurement error in subject-specific average levels of a covariate, this concept… CONTINUE READING