Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised clinical trial.

@article{1996AdjusteddoseWV,
  title={Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised clinical trial.},
  author={},
  journal={Lancet},
  year={1996},
  volume={348 9028},
  pages={633-8}
}
  • Published 1996 in Lancet
BACKGROUND Adjusted-dose warfarin is highly efficacious for prevention of ischaemic stroke in patients with atrial fibrillation (AF). However, this treatment carries a risk of bleeding and the need for frequent medical monitoring. We sought an alternative that would be safer and easier to administer to patients with AF who are at high-risk of thromboembolism. METHODS 1044 patients with AF and with at least one thromboembolic risk factor (congestive heart failure or left ventricular fractional… CONTINUE READING

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