Adjusted Analyses in Studies Addressing Therapy and Harm: Users' Guides to the Medical Literature.

Abstract

Observational studies almost always have bias because prognostic factors are unequally distributed between patients exposed or not exposed to an intervention. The standard approach to dealing with this problem is adjusted or stratified analysis. Its principle is to use measurement of risk factors to create prognostically homogeneous groups and to combine… (More)
DOI: 10.1001/jama.2016.20029

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Cite this paper

@article{Agoritsas2017AdjustedAI, title={Adjusted Analyses in Studies Addressing Therapy and Harm: Users' Guides to the Medical Literature.}, author={Thomas Agoritsas and Arnaud Merglen and Nilay D. Shah and M J O'donnell and Gordon H. Guyatt}, journal={JAMA}, year={2017}, volume={317 7}, pages={748-759} }