Adjunctive use of a subgingival controlled-release chlorhexidine chip reduces probing depth and improves attachment level compared with scaling and root planing alone.

@article{Jeffcoat1998AdjunctiveUO,
  title={Adjunctive use of a subgingival controlled-release chlorhexidine chip reduces probing depth and improves attachment level compared with scaling and root planing alone.},
  author={M K Jeffcoat and Kimberly S Krust Bray and Sebastian G. Ciancio and Andrew R. Dentino and Daniel H Fine and Jeffrey M Gordon and John C. Gunsolley and William J Killoy and R A Lowenguth and Niklas Magnusson and Steven Offenbacher and Kent G Palcanis and Howard M. Proskin and Richard D. Finkelman and Michael Flashner},
  journal={Journal of periodontology},
  year={1998},
  volume={69 9},
  pages={989-97}
}
The present studies evaluated the efficacy of a controlled-release biodegradable chlorhexidine (CHX) (2.5 mg) chip when used as an adjunct to scaling and root planing on reducing probing depth (PD) and improving clinical attachment level (CAL) in adult periodontitis. Two double-blind, randomized, placebo-controlled multi-center clinical trials (5 centers each) were conducted; pooled data are reported from all 10 centers (447 patients). At baseline, following 1 hour of scaling and root planing… CONTINUE READING