Adjunctive fluoxetine in the treatment of negative symptoms in chronic schizophrenic patients.

@article{Spina1994AdjunctiveFI,
  title={Adjunctive fluoxetine in the treatment of negative symptoms in chronic schizophrenic patients.},
  author={Edoardo Spina and P M De Domenico and C. Ruello and N Longobardo and Christina A. Gitto and Maria Ancione and Antonio Enrico Di Rosa and Achille Patrizio Caputi},
  journal={International clinical psychopharmacology},
  year={1994},
  volume={9 4},
  pages={
          281-5
        }
}
The effect of adjunctive fluoxetine on negative schizophrenic symptoms was evaluated in 34 chronic schizophrenic in-patients on maintenance therapy with neuroleptics. They received randomly, on a double-blind basis, fluoxetine (20 mg/day) or placebo for 12 weeks. In the fluoxetine group, three patients dropped out because of side effects. Negative symptoms, as measured by change on the Scale for Assessment of Negative Symptoms at the end point compared to baseline values, were significantly… CONTINUE READING
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