Adjunctive dexmedetomidine therapy in the intensive care unit: a retrospective assessment of impact on sedative and analgesic requirements, levels of sedation and analgesia, and ventilatory and hemodynamic parameters.

@article{Maclaren2007AdjunctiveDT,
  title={Adjunctive dexmedetomidine therapy in the intensive care unit: a retrospective assessment of impact on sedative and analgesic requirements, levels of sedation and analgesia, and ventilatory and hemodynamic parameters.},
  author={Robert E Maclaren and Laurel K Forrest and Tyree H Kiser},
  journal={Pharmacotherapy},
  year={2007},
  volume={27 3},
  pages={351-9}
}
STUDY OBJECTIVE To determine if adjunctive dexmedetomidine therapy in intensive care patients alters requirements for and levels of sedation and analgesia, and to describe hemodynamic and ventilatory parameters. DESIGN Retrospective, noncontrolled, descriptive study of clinical practice. SETTING Four intensive care units (ICUs; medical, surgical, neurosurgical, or burn) in a university-affiliated medical center. PATIENTS Forty patients who were already receiving sustained use of propofol… CONTINUE READING

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