Adjunctive brivaracetam for patients with refractory partial seizures: A meta-analysis of randomized placebo-controlled trials.

@article{Ma2015AdjunctiveBF,
  title={Adjunctive brivaracetam for patients with refractory partial seizures: A meta-analysis of randomized placebo-controlled trials.},
  author={Junpeng Ma and Siqing Huang and Chao You},
  journal={Epilepsy research},
  year={2015},
  volume={114},
  pages={59-65}
}
OBJECTIVE To evaluate the clinical efficacy and safety of the newer antiepileptic drug (AED), brivaracetam (BRV), as adjunctive therapy for adults with refractory partial seizures. METHODS Randomized-controlled trials (RCTs) of BRV in the treatment of refractory partial seizure were systematically reviewed and quantified using fixed- or random-effects meta-analysis. 50% responder rate, seizure free rate and adverse events in the treatment period were analyzed as outcomes for measuring… CONTINUE READING