Adjacent Lichen Sclerosis predicts local recurrence and second field tumour in women with vulvar squamous cell carcinoma.

@article{Yap2016AdjacentLS,
  title={Adjacent Lichen Sclerosis predicts local recurrence and second field tumour in women with vulvar squamous cell carcinoma.},
  author={Jason Yap and Richard I Fox and Sarah M. Leonard and Raji Ganesan and Sean T Kehoe and Christopher Dawson and Ciaran B.J. Woodman and David Michael Luesley},
  journal={Gynecologic oncology},
  year={2016},
  volume={142 3},
  pages={420-6}
}
OBJECTIVE In this study, we investigated if the presence of histologically abnormal epithelium adjacent to the primary tumour influenced the frequency, timing, and topography of local vulvar recurrences (LVR) following treatment for squamous cell carcinoma of the vulva (VSCC). METHODS The study population comprised a cohort of 201 consecutive cases with incident VSCC. LVR were categorised as local relapses (LR) if they occurred <2cm from the tumour margins, and as second field tumours (SFT… CONTINUE READING