Adiposity blunts the positive relationship of thyrotropin with proprotein convertase subtilisin-kexin type 9 levels in euthyroid subjects.

Abstract

BACKGROUND Effects of thyroid function status on lipoprotein metabolism may extend into the euthyroid range. Low-density lipoprotein (LDL) metabolism is governed by proprotein convertase subtilisin-kexin type 9 (PCSK9), which down-regulates LDL receptor expression, resulting in higher LDL cholesterol (LDL-C). Here, we tested whether plasma PCSK9 correlates… (More)
DOI: 10.1089/thy.2012.0434

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@article{Kwakernaak2013AdiposityBT, title={Adiposity blunts the positive relationship of thyrotropin with proprotein convertase subtilisin-kexin type 9 levels in euthyroid subjects.}, author={Arjan J. Kwakernaak and Gilles Lambert and Anneke C. Muller Kobold and Robin P F Dullaart}, journal={Thyroid : official journal of the American Thyroid Association}, year={2013}, volume={23 2}, pages={166-72} }