Adipose tissue remodeling in children: the link between collagen deposition and age-related adipocyte growth.

@article{Tam2012AdiposeTR,
  title={Adipose tissue remodeling in children: the link between collagen deposition and age-related adipocyte growth.},
  author={Charmaine S Tam and Joan Tordjman and Adeline Divoux and Louise A. Baur and Karine Cl{\'e}ment},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2012},
  volume={97 4},
  pages={1320-7}
}
CONTEXT Extracellular matrix (ECM) remodeling is essential for adipose tissue growth and expansion in high fat-fed mice, and there is evidence of fibrosis in adipose tissue in human obesity. OBJECTIVE The aim of the study was to explore the role of ECM remodeling in adipose tissue in healthy, growing children. RESEARCH DESIGN, SETTING, AND PARTICIPANTS: Abdominal sc adipose biopsies were obtained from 65 otherwise healthy children [57 boys; age, 5.3 ± 3.8 yr (mean ± sd)] having elective… CONTINUE READING
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