Adipose tissue macrophages: going off track during obesity

  title={Adipose tissue macrophages: going off track during obesity},
  author={Lily Boutens and Rinke Stienstra},
Inflammation originating from the adipose tissue is considered to be one of the main driving forces for the development of insulin resistance and type 2 diabetes in obese individuals. Although a plethora of different immune cells shapes adipose tissue inflammation, this review is specifically focused on the contribution of macrophages that reside in adipose tissue in lean and obese conditions. Both conventional and tissue-specific functions of adipose tissue macrophages (ATMs) in lean and obese… CONTINUE READING